Role of Positron Emission Tomography Cardiac Perfusion Imaging in Clinical Management, Prognosis, and Risk Stratification of Cardiovascular Disease

Coronary artery disease (CAD) is an important cause of morbidity and mortality worldwide. Perfusion abnormalities precede wall motion abnormalities, ECG changes, angina in the etiology CAD. myocardial perfusion imaging (MPI) can detect alterations due to pathology at sites such as endothelium, microvasculature, epicardial coronary arteries. Thus, it measures universal burden ischemic heart (IHD). Nuclear medicine MPI noninvasive modality evaluate myocardium. Positron Emission Tomography (PET) single-photon emission computed tomography (SPECT) with or without (CT) are 2 primary modalities. PET a highly sensitive inherent ability quantify absolute blood flow (MBF) variations MBF various stress agents. has immense potential change clinical management, prognosticate, risk stratify patients presenting preclinical Evidence shows that early detection followed by aggressive intervention for cardiovascular factors, reinstate perfusion. This may reduce mortality. We shall be reviewing impact CAD patients.